top of page

Esophageal & Gastric Cancer Screening and Prevention  

1. Guidelines for Screening

Risk factors for esophageal cancer:

Age 45 to 70 years

Gastroesophageal reflux disease (GERD)

Barrett’s esophagus

Smoking

Alcohol

Asian Flush Syndrome (in response to alcohol)

Bile reflux

Chewing tobacco

Achalasia

Drinking very hot liquids

Obesity

Prior radiation therapy to the chest or upper abdomen

Eating insufficient fruits and vegetables

Eating foods preserved in lye, such as lutefisk, a Nordic recipe for whitefish and some olive recipes

Being male

Tylosis

Plummer-Vinson syndrome

Caustic esophageal injury

 

Risk factors for gastric cancer:

 

H. Pylori

Atrophic gastritis

Intestinal metaplasia on endoscopic gastric biopsy

First generation Japanese living in the United States

Pernicious anemia

Prior distal gastrectomy

Lack of fresh fruits and vegetables

Eating foods prepared in salt such as pickled vegetables

Family history of gastric cancer

HNPCC

 

Screening

Esophageal cancer

 

Screening endoscopy is not appropriate for all patients with GERD

 

There is no level I evidence that screening for esophageal cancer will lower the very high mortality of the disease but cancers diagnosed in patients with Barrett’ s Esophagus who have been screened with esophagogastroscopy, tend to be at earlier stages than cancer patients who have not been screened

 

Screening patients with GERD, of whom about 10 percent are associated with Barrett’s esophagus with annual esophagoscopy. About 10% of these patients will develop esophageal cancer in their lifetime

Smoking is a strong risk factor for squamous cancers of the esophagus and to a lesser degree adenocarcinomas

 

Gastric cancer

 

There is no level 1 evidence that screening for gastric cancer will lower the very high mortality of the disease

 

Gastric cancer patients who are under the age under the age of 50 should be screened for HNPCC or Familial gastric cancer

 

2. Cancer Prevention

  

Patients with Barrett’s esophagus, and dysplasia on biopsy, may reduce their chances of esophageal cancer with treatment of their GERD and local ablative therapy to the Barrett’s disease

 

Not smoking

Quitting smoking preferably by joining a smoking cessation program

Eating more fruits and vegetables

Strang Cancer Prevention Institute has developed and updates guidelines for cancer screening and best practices for cancer prevention using guidelines of the National Cancer Institute (NCI), the National Consortium of Cancer Centers Network (NCCCN) and the American Cancer Society (ACS). Strang is synonymous with cancer screening and prevention. Strang was the first medical facility to introduce the Pap test into clinical practice which has saved millions of women's lives worldwide. Strang was opened by first lady Eleanor Roosevelt in 1933.

The information contained on this website is for educational and informational purposes only. It is not intended to be a substitute for professional medical advice, diagnosis or treatment. Always seek the advice of your physician or other qualified medical provider with any questions you may have about a medical condition. Never disregard professional medical advice or delay in seeking it because of something you have read on this site.

 

Strang assumes no responsibility to correct or update its website nor to resolve any inconsistent information that might be a part of the website.

© 2009-2026 Strang Cancer Prevention Institute. All Rights Reserved.

bottom of page